|authors ||Schutter, D.J.L.G.; Leitner, C.; Kenemans, J.L.; Honk, E.J. van|
|source ||Clinical Neurophysiology, Volume: 117 (2006), pp. 381-387|
|full text ||[Full text]|
|document type ||Article|
|disciplines ||Psychologie, Farmacie|
|abstract ||Objective: Several studies have provided evidence for the notion that the coupling between slow and fast frequency in the EEG spectrum
indicates cortico-subcortical cross-talk (CSC-ct). In addition, findings for increased limbic activation due to reduced cortical inhibition have
recently been acquired. To get further insights into these mechanisms, the current study investigated whether CSC-ct would decrease as a
function of increased slow (SW) or fast wave (FW) activity.
Methods: Resting state EEG recordings were obtained from 46 healthy, right-handed participants. CSC-ct was quantified by computing
cross-frequency correlations between the power in the slow and fast frequency range. CSC-ct was compared between groups with relatively
low and high SW activity and groups with relatively low and high FW activity.
Results: Relatively reduced SW, but not FW activity was associated with a significant coupling between slow and fast frequency EEG.
Furthermore, relatively enhanced resting state SW activity was paralleled by slow and fast frequency EEG decoupling.
Conclusions: These findings are in line with the notion that increased subcortical drive can go accompanied by reduced CSC-ct.
Significance: Cross-frequency EEG analyses might provide a unique approach to obtain novel insights into cortico-subcortical interactions in
relation to affective and cognitive behavior.
q 2005 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.
Keywords: Beta; Coupling; Cortex; Delta; EEG spectrum; Functional connectivity; Limbic system; Theta|